JN Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Neurophysiol 67: 318-331, 1992;
0022-3077/92 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Golowasch, J.
Right arrow Articles by Marder, E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Golowasch, J.
Right arrow Articles by Marder, E.

Journal of Neurophysiology, Vol 67, Issue 2 318-331, Copyright © 1992 by APS

ARTICLES

Ionic currents of the lateral pyloric neuron of the stomatogastric ganglion of the crab

J. Golowasch and E. Marder
Department of Biology, Brandeis University, Waltham, Massachusetts 02254-9110.

1. The lateral pyloric (LP) neuron is an important component of the network that generates the pyloric rhythm of the stomatogastric ganglion (STG) and is a direct target of many modulatory inputs to the STG. Our aim in this and the subsequent two papers is to describe the conductances present in this cell and to understand the role these conductances play in shaping the activity of the neuron. 2. LP neurons were studied in two-electrode voltage clamp (TEVC) in a saline solution containing tetrodotoxin (TTX) and picrotoxin (PTX) to isolate them pharmacologically from presynaptic inputs. 3. We identified six voltage-dependent ionic conductances. These include three outward currents that resemble a delayed rectifier current, a Ca(2+)-activated K+ current and an A-current similar to those seen in many other preparations. LP neurons show three inward currents, a fast TTX-sensitive current, a hyperpolarization-activated inward current, and a Ca2+ current.


This article has been cited by other articles:


Home page
 J. Neurophysiol.Home page
E. Hong, F. Gurel Kazanci, and A. A. Prinz
Different Roles of Related Currents in Fast and Slow Spiking of Model Neurons From Two Phyla
J Neurophysiol, October 1, 2008; 100(4): 2048 - 2061.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
O. Khorkova and J. Golowasch
Neuromodulators, Not Activity, Control Coordinated Expression of Ionic Currents
J. Neurosci., August 8, 2007; 27(32): 8709 - 8718.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
P. Rabbah and F. Nadim
Distinct Synaptic Dynamics of Heterogeneous Pacemaker Neurons in an Oscillatory Network
J Neurophysiol, March 1, 2007; 97(3): 2239 - 2253.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
F. Gabbiani and H. G. Krapp
Spike-Frequency Adaptation and Intrinsic Properties of an Identified, Looming-Sensitive Neuron
J Neurophysiol, December 1, 2006; 96(6): 2951 - 2962.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
J. H. Peck, E. Gaier, E. Stevens, S. Repicky, and R. M. Harris-Warrick
Amine Modulation of Ih in a Small Neural Network
J Neurophysiol, December 1, 2006; 96(6): 2931 - 2940.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
G. E. Serrano and M. W. Miller
Conditional Rhythmicity and Synchrony in a Bilateral Pair of Bursting Motor Neurons in Aplysia
J Neurophysiol, October 1, 2006; 96(4): 2056 - 2071.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
R. J. Haedo and J. Golowasch
Ionic Mechanism Underlying Recovery of Rhythmic Activity in Adult Isolated Neurons
J Neurophysiol, October 1, 2006; 96(4): 1860 - 1876.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
G. Zhong, M. Diaz-Rios, and R. M. Harris-Warrick
Intrinsic and functional differences among commissural interneurons during fictive locomotion and serotonergic modulation in the neonatal mouse.
J. Neurosci., June 14, 2006; 26(24): 6509 - 6517.
[Abstract] [Full Text] [PDF]

Home page
 Biol. Bull.Home page
M. Diaz-Rios and M. W. Miller
Target-Specific Regulation of Synaptic Efficacy in the Feeding Central Pattern Generator of Aplysia: Potential Substrates for Behavioral Plasticity?
Biol. Bull., June 1, 2006; 210(3): 215 - 229.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
T. Le, D. R. Verley, J.-M. Goaillard, D. I. Messinger, A. E. Christie, and J. T. Birmingham
Bistable Behavior Originating in the Axon of a Crustacean Motor Neuron
J Neurophysiol, March 1, 2006; 95(3): 1356 - 1368.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
M. Gruhn, J. Guckenheimer, B. Land, and R. M. Harris-Warrick
Dopamine Modulation of Two Delayed Rectifier Potassium Currents in a Small Neural Network
J Neurophysiol, October 1, 2005; 94(4): 2888 - 2900.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
P. Rabbah, J. Golowasch, and F. Nadim
Effect of Electrical Coupling on Ionic Current and Synaptic Potential Measurements
J Neurophysiol, July 1, 2005; 94(1): 519 - 530.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
T. Adachi, D. M. Robinson, G. B. Miles, and G. D. Funk
Noradrenergic modulation of XII motoneuron inspiratory activity does not involve {alpha}2-receptor inhibition of the Ih current or presynaptic glutamate release
J Appl Physiol, April 1, 2005; 98(4): 1297 - 1308.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
D. Bucher, A. A. Prinz, and E. Marder
Animal-to-Animal Variability in Motor Pattern Production in Adults and during Growth
J. Neurosci., February 16, 2005; 25(7): 1611 - 1619.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
I. Greenberg and Y. Manor
Synaptic Depression in Conjunction With A-Current Channels Promote Phase Constancy in a Rhythmic Network
J Neurophysiol, February 1, 2005; 93(2): 656 - 677.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
A. A. Prinz, C. P. Billimoria, and E. Marder
Alternative to Hand-Tuning Conductance-Based Models: Construction and Analysis of Databases of Model Neurons
J Neurophysiol, December 1, 2003; 90(6): 3998 - 4015.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
Y. Zhang, R. Oliva, G. Gisselmann, H. Hatt, J. Guckenheimer, and R. M. Harris-Warrick
Overexpression of a Hyperpolarization-Activated Cation Current (Ih) Channel Gene Modifies the Firing Activity of Identified Motor Neurons in a Small Neural Network
J. Neurosci., October 8, 2003; 23(27): 9059 - 9067.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
B. R. Johnson, P. Kloppenburg, and R. M. Harris-Warrick
Dopamine Modulation of Calcium Currents in Pyloric Neurons of the Lobster Stomatogastric Ganglion
J Neurophysiol, August 1, 2003; 90(2): 631 - 643.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
B. Mulloney
During Fictive Locomotion, Graded Synaptic Currents Drive Bursts of Impulses in Swimmeret Motor Neurons
J. Neurosci., July 2, 2003; 23(13): 5953 - 5962.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
R. Nargeot
Voltage-Dependent Switching of Sensorimotor Integration by a Lobster Central Pattern Generator
J. Neurosci., June 15, 2003; 23(12): 4803 - 4808.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
M. Thoby-Brisson and J. Simmers
Long-Term Neuromodulatory Regulation of a Motor Pattern-Generating Network: Maintenance of Synaptic Efficacy and Oscillatory Properties
J Neurophysiol, December 1, 2002; 88(6): 2942 - 2953.
[Abstract] [Full Text] [PDF]

Home page
 JGPHome page
A. Bucchi, M. Baruscotti, and D. DiFrancesco
Current-dependent Block of Rabbit Sino-Atrial Node If Channels by Ivabradine
J. Gen. Physiol., June 10, 2002; 120(1): 1 - 13.
[Abstract] [Full Text] [PDF]

Home page
 Biol. Bull.Home page
I. M. Cooke
Reliable, Responsive Pacemaking and Pattern Generation With Minimal Cell Numbers: the Crustacean Cardiac Ganglion
Biol. Bull., April 1, 2002; 202(2): 108 - 136.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
A. Mizrahi, P. S. Dickinson, P. Kloppenburg, V. Fenelon, D. J. Baro, R. M. Harris-Warrick, P. Meyrand, and J. Simmers
Long-Term Maintenance of Channel Distribution in a Central Pattern Generator Neuron by Neuromodulatory Inputs Revealed by Decentralization in Organ Culture
J. Neurosci., September 15, 2001; 21(18): 7331 - 7339.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
D. J. Baro, A. Ayali, L. French, N. L. Scholz, J. Labenia, C. C. Lanning, K. Graubard, and R. M. Harris-Warrick
Molecular Underpinnings of Motor Pattern Generation: Differential Targeting of Shal and Shaker in the Pyloric Motor System
J. Neurosci., September 1, 2000; 20(17): 6619 - 6630.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
M. Thoby-Brisson, P. Telgkamp, and J.-M. Ramirez
The Role of the Hyperpolarization-Activated Current in Modulating Rhythmic Activity in the Isolated Respiratory Network of Mice
J. Neurosci., April 15, 2000; 20(8): 2994 - 3005.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
V. Morisset and F. Nagy
Ionic Basis for Plateau Potentials in Deep Dorsal Horn Neurons of the Rat Spinal Cord
J. Neurosci., September 1, 1999; 19(17): 7309 - 7316.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
D. M. Blitz and M. P. Nusbaum
Distinct Functions for Cotransmitters Mediating Motor Pattern Selection
J. Neurosci., August 15, 1999; 19(16): 6774 - 6783.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
L. M. Hurley and K. Graubard
Pharmacologically and Functionally Distinct Calcium Currents of Stomatogastric Neurons
J Neurophysiol, April 1, 1998; 79(4): 2070 - 2081.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
Z. Liu, J. Golowasch, E. Marder, and L. F. Abbott
A Model Neuron with Activity-Dependent Conductances Regulated by Multiple Calcium Sensors
J. Neurosci., April 1, 1998; 18(7): 2309 - 2320.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
F. M. Kuenzi and N. Dale
The Pharmacology and Roles of two K+ Channels in Motor Pattern Generation in the Xenopus Embryo
J. Neurosci., February 15, 1998; 18(4): 1602 - 1612.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
O. H. Olsen and R. L. Calabrese
Activation of Intrinsic and Synaptic Currents in Leech Heart Interneurons by Realistic Waveforms
J. Neurosci., August 15, 1996; 16(16): 4958 - 4970.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
G LeMasson, E Marder, and L. Abbott
Activity-dependent regulation of conductances in model neurons
Science, March 26, 1993; 259(5103): 1915 - 1917.
[Abstract] [PDF]

Home page
 J. Neurosci.Home page
J. Golowasch, L. F. Abbott, and E. Marder
Activity-Dependent Regulation of Potassium Currents in an Identified Neuron of the Stomatogastric Ganglion of the Crab Cancer borealis
J. Neurosci., October 15, 1999; 19(20): RC33 - RC33.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online