JN Track the topics, authors and articles important to you
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Neurophysiol 60: 232-262, 1988;
0022-3077/88 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Moschovakis, A. K.
Right arrow Articles by Highstein, S. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Moschovakis, A. K.
Right arrow Articles by Highstein, S. M.

Journal of Neurophysiology, Vol 60, Issue 1 232-262, Copyright © 1988 by APS

ARTICLES

Structure-function relationships in the primate superior colliculus. I. Morphological classification of efferent neurons

A. K. Moschovakis, A. B. Karabelas and S. M. Highstein
Department of Otolaryngology, Washington University School of Medicine, St. Louis, Missouri 63110.

1. Neurons in the superior colliculus (SC) of anesthetized paralyzed squirrel monkeys were injected intracellularly with horseradish peroxidase (HRP) to establish a morphological classification of tectal efferent neurons in this species. These neurons were physiologically identified by their antidromic responses following stimulation of the contralateral predorsal bundle or SC. These cells also responded with postsynaptic potentials to stimulation of the ipsilateral substantia nigra and cerebral peduncle and the contralateral tectum. 2. Quantitative light microscopic analysis of the somatodendritic profiles and axonal trajectories of 27 recovered cells revealed the existence of three major groups of tectal efferent neurons: L (n = 7), X (n = 8), and T (n = 12). 3. L neurons are small or medium size cells with relatively elaborate dendritic trees and are located mainly in the superficial layers of the SC. They participate in the ipsilateral descending and dorsal ascending tectofugal bundles. Intrinsic collaterals of L axons deploy a large number of boutons both near the parent cell body and more ventrally within the deeper tectal layers. 4. X neurons are mostly large in size and multipolar in shape with relatively complex dendritic trees. Their cell bodies are situated mainly in the stratum griseum intermedium and occasionally in the stratum opticum. Axons of X neurons participate in the crossed descending and ipsilateral ventral ascending projections of the SC. In addition, the axonal system of about half of the X neurons includes recurrent collaterals. 5. T neurons are located mainly in the ventral stratum opticum and the dorsal stratum griseum intermedium. They have small or medium-sized, trapezoid or ovoid cell bodies and relatively simple radiating or vertical dendritic trees. Their axons usually participate in two of the major tectofugal bundles besides providing a commissural component and recurrent collaterals. 6. Morphological details revealed in the present study support the notion that distinct tectofugal axonal systems originate from efferent neurons of the primate SC that differ both as to their location in the tectum as well as the appearance of their somata and dendritic trees. The resulting morphological classification of tectal efferent cells provides a framework for the analysis of tectal function in terms of populations of identified neurons.


This article has been cited by other articles:


Home page
 J. Neurosci.Home page
K. Kaneda, K. Isa, Y. Yanagawa, and T. Isa
Nigral Inhibition of GABAergic Neurons in Mouse Superior Colliculus
J. Neurosci., October 22, 2008; 28(43): 11071 - 11078.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
S. Rezvani and B. D. Corneil
Recruitment of a Head-Turning Synergy by Low-Frequency Activity in the Primate Superior Colliculus
J Neurophysiol, July 1, 2008; 100(1): 397 - 411.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
X. Li and M. A. Basso
Preparing to Move Increases the Sensitivity of Superior Colliculus Neurons
J. Neurosci., April 23, 2008; 28(17): 4561 - 4577.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
B. Kim and M. A. Basso
Saccade Target Selection in the Superior Colliculus: A Signal Detection Theory Approach
J. Neurosci., March 19, 2008; 28(12): 2991 - 3007.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
M. Takahashi, Y. Sugiuchi, and Y. Shinoda
Commissural Mirror-Symmetric Excitation and Reciprocal Inhibition Between the Two Superior Colliculi and Their Roles in Vertical and Horizontal Eye Movements
J Neurophysiol, November 1, 2007; 98(5): 2664 - 2682.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
M. A. Basso and P. Liu
Context-Dependent Effects of Substantia Nigra Stimulation on Eye Movements
J Neurophysiol, June 1, 2007; 97(6): 4129 - 4142.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
Y. Kojima, K. Yoshida, and Y. Iwamoto
Microstimulation of the Midbrain Tegmentum Creates Learning Signals for Saccade Adaptation
J. Neurosci., April 4, 2007; 27(14): 3759 - 3767.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
P. Lee and W. C. Hall
An in vitro study of horizontal connections in the intermediate layer of the superior colliculus.
J. Neurosci., May 3, 2006; 26(18): 4763 - 4768.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
W. Jiang, H. Jiang, and B. E. Stein
Neonatal Cortical Ablation Disrupts Multisensory Development in Superior Colliculus
J Neurophysiol, March 1, 2006; 95(3): 1380 - 1396.
[Abstract] [Full Text] [PDF]

Home page
 J. Physiol.Home page
J. A. Cromer and D. M. Waitzman
Neurones associated with saccade metrics in the monkey central mesencephalic reticular formation
J. Physiol., February 1, 2006; 570(3): 507 - 523.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
Y. Saito and T. Isa
Organization of Interlaminar Interactions in the Rat Superior Colliculus
J Neurophysiol, May 1, 2005; 93(5): 2898 - 2907.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
Y. Saito and T. Isa
Laminar Specific Distribution of Lateral Excitatory Connections in the Rat Superior Colliculus
J Neurophysiol, December 1, 2004; 92(6): 3500 - 3510.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
R. J. Krauzlis
Activity of Rostral Superior Colliculus Neurons During Passive and Active Viewing of Motion
J Neurophysiol, August 1, 2004; 92(2): 949 - 958.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
M. C. Helms, G. Ozen, and W. C. Hall
Organization of the Intermediate Gray Layer of the Superior Colliculus. I. Intrinsic Vertical Connections
J Neurophysiol, April 1, 2004; 91(4): 1706 - 1715.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
J. O. Helminski and M. A. Segraves
Macaque Frontal Eye Field Input to Saccade-Related Neurons in the Superior Colliculus
J Neurophysiol, August 1, 2003; 90(2): 1046 - 1062.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
T. P. Doubell, I. Skaliora, J. Baron, and A. J. King
Functional Connectivity between the Superficial and Deeper Layers of the Superior Colliculus: An Anatomical Substrate for Sensorimotor Integration
J. Neurosci., July 23, 2003; 23(16): 6596 - 6607.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
Y. Saito and T. Isa
Local Excitatory Network and NMDA Receptor Activation Generate a Synchronous and Bursting Command from the Superior Colliculus
J. Neurosci., July 2, 2003; 23(13): 5854 - 5864.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
B. D. Corneil, E. Olivier, and D. P. Munoz
Neck Muscle Responses to Stimulation of Monkey Superior Colliculus. I. Topography and Manipulation of Stimulation Parameters
J Neurophysiol, October 1, 2002; 88(4): 1980 - 1999.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
M. Pare and R. H. Wurtz
Progression in Neuronal Processing for Saccadic Eye Movements From Parietal Cortex Area LIP to Superior Colliculus
J Neurophysiol, June 1, 2001; 85(6): 2545 - 2562.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
R. J. Krauzlis, M. A. Basso, and R. H. Wurtz
Discharge Properties of Neurons in the Rostral Superior Colliculus of the Monkey During Smooth-Pursuit Eye Movements
J Neurophysiol, August 1, 2000; 84(2): 876 - 891.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
G. Ozen, G. J. Augustine, and W. C. Hall
Contribution of Superficial Layer Neurons to Premotor Bursts in the Superior Colliculus
J Neurophysiol, July 1, 2000; 84(1): 460 - 471.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
A. M. Brichta and J. M. Goldberg
Morphological Identification of Physiologically Characterized Afferents Innervating the Turtle Posterior Crista
J Neurophysiol, March 1, 2000; 83(3): 1202 - 1223.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
N. J. Gandhi and E. L. Keller
Comparison of Saccades Perturbed by Stimulation of the Rostral Superior Colliculus, the Caudal Superior Colliculus, and the Omnipause Neuron Region
J Neurophysiol, December 1, 1999; 82(6): 3236 - 3253.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
K. Yoshida, Y. Iwamoto, S. Chimoto, and H. Shimazu
Saccade-Related Inhibitory Input to Pontine Omnipause Neurons: An Intracellular Study in Alert Cats
J Neurophysiol, September 1, 1999; 82(3): 1198 - 1208.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
Y. Saito and T. Isa
Electrophysiological and Morphological Properties of Neurons in the Rat Superior Colliculus. I. Neurons in the Intermediate Layer
J Neurophysiol, August 1, 1999; 82(2): 754 - 767.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
M. A. Sommer and R. H. Wurtz
Frontal Eye Field Neurons Orthodromically Activated From the Superior Colliculus
J Neurophysiol, December 1, 1998; 80(6): 3331 - 3335.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
A. J. King, J. W. H. Schnupp, and I. D. Thompson
Signals from the Superficial Layers of the Superior Colliculus Enable the Development of the Auditory Space Map in the Deeper Layers
J. Neurosci., November 15, 1998; 18(22): 9394 - 9408.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
E. M. Klier and J. D. Crawford
Human Oculomotor System Accounts for 3-D Eye Orientation in the Visual-Motor Transformation for Saccades
J Neurophysiol, November 1, 1998; 80(5): 2274 - 2294.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
D. P. Munoz and P. J. Istvan
Lateral Inhibitory Interactions in the Intermediate Layers of the Monkey Superior Colliculus
J Neurophysiol, March 1, 1998; 79(3): 1193 - 1209.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
M. A. Meredith and A. S. Ramoa
Intrinsic Circuitry of the Superior Colliculus: Pharmacophysiological Identification of Horizontally Oriented Inhibitory Interneurons
J Neurophysiol, March 1, 1998; 79(3): 1597 - 1602.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
S. Everling, M. Pare, M. C. Dorris, and D. P. Munoz
Comparison of the Discharge Characteristics of Brain Stem Omnipause Neurons and Superior Colliculus Fixation Neurons in Monkey: Implications for Control of Fixation and Saccade Behavior
J Neurophysiol, February 1, 1998; 79(2): 511 - 528.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
S. Grossberg, K. Roberts, M. Aguilar, and D. Bullock
A Neural Model of Multimodal Adaptive Saccadic Eye Movement Control by Superior Colliculus
J. Neurosci., December 15, 1997; 17(24): 9706 - 9725.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
P. H. Lee, M. C. Helms, G. J. Augustine, and W. C. Hall
Role of intrinsic synaptic circuitry in collicular sensorimotor integration
PNAS, November 25, 1997; 94(24): 13299 - 13304.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurophysiol.Home page
A. Handel and P. W. Glimcher
Response Properties of Saccade-Related Burst Neurons in the Central Mesencephalic Reticular Formation
J Neurophysiol, October 1, 1997; 78(4): 2164 - 2175.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online