| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Journal of Neurophysiology, Vol 53, Issue 2 466-480, Copyright © 1985 by APS
ARTICLES |
P. A. Getting and M. S. Dekin
Swimming behavior in the marine mollusc Tritonia diomedea is episodic, consisting of a series of alternating dorsal and ventral flexions initiated by a brief sensory stimulus. The swim motor pattern is generated by a network formed of four groups of premotor interneurons: cerebral cell 2 (C2), dorsal swim interneurons (DSIs), and two types of ventral swim interneurons (VSI-A and VSI-B). The initiation and maintenance of swimming depends on the establishment of a long-lasting ramp depolarization in both the premotor, pattern-generating interneurons, and the motor neurons (i.e., flexion neurons). Voltage clamp was used to measure the membrane current responsible for the ramp depolarization. In all cell classes the current had two components: a tonic inward current, which decayed as the swim progressed, and phasic inward current waves, which provided the synaptic drive during each swim burst. The ramp current in the flexion neurons and in C2 was generated largely by activity within the interneuronal pattern-generating network (PGN). The ramp current could be mimicked by driving activity in the pattern-generating interneurons. In VSI-B, the tonic component of the ramp current was independent of activity within the PGN and appeared to be derived from the long-lasting effect of an extrinsic input. The phasic components of the ramp, however, were dependent on PGN activity. The phasic inward current waves were blocked when pattern generation was prevented. In addition, phasic inward currents similar to those occurring during swimming could be produced by driving the C2. The tonic component of the ramp current in a DSI was dependent both on extrinsic inputs and PGN activity. Extrinsic inputs appeared to control the first 10-15 s of the tonic current. At longer times, activity within the DSI population itself maintained the ramp current. When one DSI was driven in a quiescent preparation, all other DSIs were inhibited, yet the DSIs are known to be coupled by monosynaptic, reciprocal excitatory synapses. This effect could be explained by the action of an unidentified inhibitory interneuron (I-neuron), which was excited by DSIs and in turn inhibited all other DSIs. The DSIs were therefore coupled reciprocally by both monosynaptic excitation and polysynaptic inhibition. Activity in C2 switched the DSI-DSI interaction from inhibition to excitation by inhibiting the I-neuron.(ABSTRACT TRUNCATED AT 400 WORDS)
This article has been cited by other articles:
|
|
 |
|
  T. Crow and L.-M. Tian Sensory Regulation of Network Components Underlying Ciliary Locomotion in Hermissenda J Neurophysiol, November 1, 2008; 100(5): 2496 - 2506. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Sasaki, J. Jing, M. R. Due, and K. R. Weiss An Input-Representing Interneuron Regulates Spike Timing and Thereby Phase Switching in a Motor Network J. Neurosci., February 20, 2008; 28(8): 1916 - 1928. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W.-C. Li, B. Sautois, A. Roberts, and S. R. Soffe Reconfiguration of a Vertebrate Motor Network: Specific Neuron Recruitment and Context-Dependent Synaptic Plasticity J. Neurosci., November 7, 2007; 27(45): 12267 - 12276. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J.-s. Wu, M. R. Due, K. Sasaki, A. Proekt, J. Jing, and K. R. Weiss State Dependence of Spike Timing and Neuronal Function in a Motor Pattern Generating Network J. Neurosci., October 3, 2007; 27(40): 10818 - 10831. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. J. Calin-Jageman, M. J. Tunstall, B. D. Mensh, P. S. Katz, and W. N. Frost Parameter Space Analysis Suggests Multi-Site Plasticity Contributes to Motor Pattern Initiation in Tritonia J Neurophysiol, October 1, 2007; 98(4): 2382 - 2398. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. P. Norekian and A. Y. Malyshev Neural Mechanisms Underlying Co-Activation of Functionally Antagonistic Motoneurons During a Clione Feeding Behavior J Neurophysiol, April 1, 2006; 95(4): 2560 - 2569. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Sakurai, N. R. Darghouth, R. J. Butera, and P. S. Katz Serotonergic Enhancement of a 4-AP-Sensitive Current Mediates the Synaptic Depression Phase of Spike Timing-Dependent Neuromodulation J. Neurosci., February 15, 2006; 26(7): 2010 - 2021. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Ch. Ludwar, S. Westmark, A. Buschges, and J. Schmidt Modulation of Membrane Potential in Mesothoracic Moto- and Interneurons During Stick Insect Front-Leg Walking J Neurophysiol, October 1, 2005; 94(4): 2772 - 2784. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. S. Katz, A. Sakurai, S. Clemens, and D. Davis Cycle Period of a Network Oscillator Is Independent of Membrane Potential and Spiking Activity in Individual Central Pattern Generator Neurons J Neurophysiol, September 1, 2004; 92(3): 1904 - 1917. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Jing and R. Gillette Directional Avoidance Turns Encoded by Single Interneurons and Sustained by Multifunctional Serotonergic Cells J. Neurosci., April 1, 2003; 23(7): 3039 - 3051. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Clemens and P. S. Katz G Protein Signaling in a Neuronal Network is Necessary for Rhythmic Motor Pattern Production J Neurophysiol, February 1, 2003; 89(2): 762 - 772. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Y. Malyshev and T. P. Norekian Phase-Locked Coordination Between Two Rhythmically Active Feeding Structures in the Mollusk Clione limacina. I. Motor Neurons J Neurophysiol, June 1, 2002; 87(6): 2996 - 3005. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. R. Popescu and W. N. Frost Highly Dissimilar Behaviors Mediated by a Multifunctional Network in the Marine Mollusk Tritonia diomedea J. Neurosci., March 1, 2002; 22(5): 1985 - 1993. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. T. Morgan, J. Jing, F. S. Vilim, and K. R. Weiss Interneuronal and Peptidergic Control of Motor Pattern Switching in Aplysia J Neurophysiol, January 1, 2002; 87(1): 49 - 61. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W. N. Frost, T. A. Hoppe, J. Wang, and L.-M. Tian Swim Initiation Neurons in Tritonia diomedea Integr. Comp. Biol., August 1, 2001; 41(4): 952 - 961. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. S. Katz, D. J. Fickbohm, and C. P. Lynn-Bullock Evidence that the Central Pattern Generator for Swimming in Tritonia Arose from a Non-Rhythmic Neuromodulatory Arousal System: Implications for the Evolution of Specialized Behavior Integr. Comp. Biol., August 1, 2001; 41(4): 962 - 975. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Gillette and J. Jing The Role of the Escape Swim Motor Network in the Organization of Behavioral Hierarchy and Arousal in Pleurobranchaea Integr. Comp. Biol., August 1, 2001; 41(4): 983 - 992. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Jing and R. Gillette Escape Swim Network Interneurons Have Diverse Roles in Behavioral Switching and Putative Arousal in Pleurobranchaea J Neurophysiol, March 1, 2000; 83(3): 1346 - 1355. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. J. Fickbohm and P. S. Katz Paradoxical Actions of the Serotonin Precursor 5-hydroxytryptophan on the Activity of Identified Serotonergic Neurons in a Simple Motor Circuit J. Neurosci., February 15, 2000; 20(4): 1622 - 1634. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. Dragoi and M. Sur Dynamic Properties of Recurrent Inhibition in Primary Visual Cortex: Contrast and Orientation Dependence of Contextual Effects J Neurophysiol, February 1, 2000; 83(2): 1019 - 1030. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Le Ray and D. Cattaert Active Motor Neurons Potentiate Their Own Sensory Inputs via Glutamate-Induced Long-Term Potentiation J. Neurosci., February 15, 1999; 19(4): 1473 - 1483. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. S. Katz and W. N. Frost Removal of Spike Frequency Adaptation via Neuromodulation Intrinsic to the Tritonia Escape Swim Central Pattern Generator J. Neurosci., October 15, 1997; 17(20): 7703 - 7713. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. G. Morris and S. L. Hooper Muscle Response to Changing Neuronal Input in the Lobster (Panulirus interruptus) Stomatogastric System: Spike Number- versus Spike Frequency-Dependent Domains J. Neurosci., August 1, 1997; 17(15): 5956 - 5971. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. S. Dickinson, W. P. Fairfield, J. R. Hetling, and J. Hauptman Neurotransmitter Interactions in the Stomatogastric System of the Spiny Lobster: One Peptide Alters the Response of a Central Pattern Generator to a Second Peptide J Neurophysiol, February 1, 1997; 77(2): 599 - 610. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. K. Deuel and B. P. Doar Developmental Manual Dyspraxia: A Lesson in Mind and Brain J Child Neurol, January 1, 1992; 7(1): 99 - 103. [Abstract] [PDF]
|
|
|
|
 |
|
 S. Hooper and M Moulins Switching of a neuron from one network to another by sensory-induced changes in membrane properties Science, June 30, 1989; 244(4912): 1587 - 1589. [Abstract] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Visit Other APS Journals Online |
